Omega Therapeutics
20 Acorn Park Drive
STE 400
Cambridge
MA
02140
United States
Tel: (617) 949-4359
Website: https://omegatherapeutics.com/
Email: Contact@omegatherapeutics.com
About Omega Therapeutics
Omega Therapeutics is a publicly held, development-stage biotechnology company pioneering a new class of DNA-sequence-targeting, mRNA-encoded therapeutics to transform human medicine. The OMEGA Epigenomic Programming™ platform harnesses the power of epigenetics, the mechanism that systematically controls every aspect of an organism’s life from cell genesis, to growth and differentiation. The OMEGA platform has identified thousands of novel DNA-sequence-based epigenomic targets within Insulated Genomic Domains (IGDs), referred to as EpiZips™. IGDs represent the three-dimensional, distinct, and evolutionarily conserved architecture of the genome, and are the fundamental structural and functional units of gene control and cell differentiation. They act as the “control room” of biology. The OMEGA platform examines alterations in IGDs leading to aberrant gene expression, a cause of most disease. It then leverages its database of EpiZips to identify appropriate intervention points within the IGDs and rationally designs biologically engineered, modular, and programmable mRNA-encoded epigenetic medicines, called Omega Epigenomic Controllers™, to target EpiZips for Precision Genomic Control™. With its computation- and data-first approach, Omega Therapeutics is currently advancing a broad pipeline of programs that span regenerative medicine, multigenic diseases including immunology, oncology, and select monogenic diseases.
54 articles about Omega Therapeutics
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Omega Therapeutics Reports First Quarter 2023 Financial Results and Highlights Recent Company Progress
5/4/2023
Omega Therapeutics today announced financial results for the first quarter ended March 31, 2023, and highlighted recent Company progress.
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Omega Therapeutics to Present New Preclinical Data at the American Society of Clinical Oncology 2023 Annual Meeting
4/27/2023
Omega Therapeutics, Inc. (Nasdaq: OMGA) (“Omega”) today announced that it will present new preclinical data related to its MYC-HCC and MYC-NSCLC programs at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting taking place in Chicago, Illinois, June 2 – 6, 2023.
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Omega Therapeutics Announces Clinical Supply Agreement to Evaluate the Combination of OTX-2002 and Atezolizumab in Hepatocellular Carcinoma
3/30/2023
Omega Therapeutics, Inc. (Nasdaq: OMGA) (“Omega”) today announced a clinical supply agreement with Roche to evaluate OTX-2002, its lead candidate in development for the treatment of MYC-driven hepatocellular carcinoma (HCC), in combination with Roche’s anti-PD-L1 therapy, atezolizumab, as part of Omega’s Phase 1/2 MYCHELANGELO™ I clinical trial.
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Omega Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Corporate Update
3/1/2023
Omega Therapeutics, Inc. today announced financial results for the fourth quarter and full year ended December 31, 2022 and provided a corporate update.
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Omega Therapeutics Announces $40 Million Registered Direct Offering of Common Stock
2/23/2023
Omega Therapeutics, Inc. today announced that it has entered into a securities purchase agreement with investors in a registered direct offering of 6,920,415 shares of common stock (the “Shares”) at a purchase price of $5.78 per share, resulting in gross proceeds of approximately $40 million.
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Omega Therapeutics to Participate in the Piper Sandler 34th Annual Healthcare Conference
11/17/2022
Omega Therapeutics, Inc. today announced that management will participate in a fireside chat at the Piper Sandler 34th Annual Healthcare Conference on Thursday, December 1, 2022, at 8:00 a.m. ET.
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Omega Therapeutics Named One of BioSpace's 2023 Best Places to Work
11/15/2022
Omega Therapeutics, Inc. (Nasdaq: OMGA) ("Omega"), a clinical-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as a new class of programmable epigenetic medicines, today announced that it has been named among BioSpace's Best Places to Work.
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Omega Therapeutics Reports Third Quarter 2022 Financial Results and Recent Corporate Highlights
11/8/2022
Omega Therapeutics, Inc. today announced financial results for the third quarter ended September 30, 2022 and highlighted recent Company progress.
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Omega Therapeutics to Participate in the Jefferies 2022 London Healthcare Conference
11/3/2022
Omega Therapeutics, Inc. announced that management will participate in a fireside chat at the Jefferies London Healthcare Conference on Tuesday, November 15, 2022, at 11:30 a.m. GMT.
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Omega Therapeutics Receives Orphan Drug Designation for OTX-2002 for the Treatment of Hepatocellular Carcinoma
11/2/2022
Omega Therapeutics, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for OTX-2002, the company's first-in-class epigenomic controller engineered to downregulate c-Myc (MYC), for the treatment of hepatocellular carcinoma (HCC).
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Omega Therapeutics Announces First Patient Dosed in Landmark MYCHELANGELO™ I Trial of OTX-2002 in Hepatocellular Carcinoma and Other Solid Tumor Types Associated with the MYC Oncogene
10/27/2022
Omega Therapeutics, Inc. (NASDAQ: OMGA) ("Omega") today announced dosing of the first patient in its Phase 1/2 MYCHELANGELO™ I trial evaluating OTX-2002 for the treatment of relapsed or refractory hepatocellular carcinoma (HCC) and other solid tumor types associated with c-Myc (MYC) oncogene overexpression. OTX-2002.
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Omega Therapeutics to Participate in Two Upcoming Investor Conferences
9/26/2022
Omega Therapeutics, Inc. today announced that members of management will participate in two upcoming investor conferences.
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BioSpace spoke with three CEOs: Alto Neuroscience’s Dr. Amit Etkin, Omega Therapeutics’ Mahesh Karande and Rain Therapeutics’ Avanish Vellanki about their companies' employment growth.
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Omega Therapeutics to Participate in the H.C. Wainwright 24th Annual Global Investment Conference
9/6/2022
Omega Therapeutics, Inc. (NASDAQ: OMGA) ("Omega"), today announced that management will participate in a fireside chat at the H.C. Wainwright 24th Annual Global Investment Conference.
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Omega Therapeutics Announces Appointment of Rainer Boehm to its Board of Directors
9/1/2022
Omega Therapeutics, Inc. (Nasdaq: OMGA) ("Omega"), today announced the appointment of Rainer Boehm as an independent director to its Board of Directors.
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Omega Therapeutics Reports Second Quarter 2022 Financial Results and Highlights Recent Company Progress
8/4/2022
Omega Therapeutics, Inc. announced financial results for the second quarter ended June 30, 2022, and highlighted recent Company progress.
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Omega Therapeutics to Participate in the 2022 Wedbush PacGrow Healthcare Conference
8/3/2022
Omega Therapeutics, Inc., a clinical-stage biotechnology company pioneering the first systematic approach to use mRNA therapeutics as programmable epigenetic medicines by leveraging its OMEGA Epigenomic Programing™ platform, announced that Thomas McCauley, Chief Scientific Officer, will participate in a fireside chat at the 2022 Wedbush PacGrow Healthcare Conference on August 10, 2022, at 8 a.m. ET.
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Omega Therapeutics announced Thursday that the Investigational New Drug (IND) application for its hepatocellular carcinoma (HCC) candidate OTX-2002 has been granted by the FDA.
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Omega Therapeutics Announces FDA Clearance of IND Application for OTX-2002, First Omega Epigenomic Controller, for MYC Driven Hepatocellular Carcinoma
7/14/2022
Omega Therapeutics, Inc. (Nasdaq: OMGA) ("Omega"), today announced that it has received clearance of its Investigational New Drug (IND) application from the U.S. Food and Drug Administration (FDA) to initiate a Phase 1/2, first-in-human, clinical study of OTX-2002 for the treatment of hepatocellular carcinoma (HCC).
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Omega Therapeutics Presents New Preclinical Data Supporting the First Epigenomic Controller, OTX-2002, as a Potential Therapeutic Approach in Hepatocellular Carcinoma at the ESMO 2022 World Congress on Gastrointestinal Cancer
6/30/2022
Omega Therapeutics, Inc. announces the presentation of new preclinical data on its lead product candidate, OTX-2002, to regulate expression of the c-Myc (MYC) oncogene through epigenetic modulation in multiple models of hepatocellular carcinoma (HCC) in a poster presentation at the European Society of Medical Oncology (ESMO) 2022 World Congress on Gastrointestinal (GI) Cancer, taking place in Barcelona, Spain, June 29 – July 2, 2022.